{"id":34,"date":"2023-05-24T23:46:03","date_gmt":"2023-05-24T23:46:03","guid":{"rendered":"https:\/\/faculty.engineering.asu.edu\/kang\/?page_id=34"},"modified":"2023-05-24T23:47:09","modified_gmt":"2023-05-24T23:47:09","slug":"bionanotechnology","status":"publish","type":"page","link":"https:\/\/faculty.engineering.asu.edu\/kang\/bionanotechnology\/","title":{"rendered":"Bionanotechnology"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p>Micro\/nano-scale biotools for cell transfection and analysis are being developed to achieve cell-specific experimental capabilities and localized cell-tool interfaces. This allows for minimal perturbation to cells and unprecedented spatial resolution, which is essential for fundamental cell studies.<\/p>\n\n\n\n<p>The ability to precisely deliver molecules into single cells is of great interest to biotechnology researchers for advancing applications in therapeutics, diagnostics, and drug delivery toward the promise of personalized medicine. The use of bulk electroporation techniques for cell transfection has increased significantly in the last decade, but the technique is nonspecific and requires high voltage, resulting in variable efficiency and low cell viability. Our lab is interested in developing \u00a0a new biotool for cell analysis and manipulation.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Selected papers<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>W. Kang, R. McNaughton, and H. Espinosa, In Vitro Micro- and Nano-scale Technologies for Delivery into Adherent Cells, 34 (8), 665\u2013678, Trends in Biotechnology, 2016, (Highlighted in BRIC.org, IF: 12.1).<\/li>\n\n\n\n<li>\u200b\u200bS. Nathamgari, B. Dong, F. Zhou, W. Kang, J. Giraldo-Vela, T. McGuire, R. McNaughton, C. Sun, J. Kessler, H. Espinosa, Isolating single cells in a neurosphere assay using inertial microfluidics, 15 (24), 4591-4597, Lab on a Chip, 2015&nbsp;(Highlighted in Science Daily, nanowerk, Biology News Net, Science Newsline, EurekAlert, Phys.org, IF: 5.8).<\/li>\n\n\n\n<li>\u200b\u200bJ. Giraldo-Vela, W. Kang, R. McNaughton, A. Chen, A. Tsourkas, and H. Espinosa, Single Cell Detection of mRNA Expression Using Nanofountain Probe Electroporated Molecular Beacons, 11 (20), 2386-2391, Small, 2015, (Featured as the cover article, IF: 8.4).<\/li>\n\n\n\n<li>\u200b\u200bW. Kang, J. Giraldo-Vela, S. Nathamgari, T. McGuire, R. McNaughton, J. Kessler, and H. Espinosa, Transfection of Postmitotic Neurons Using a Microfluidic Localized Electroporation Device, 14(23), 4486-4495, Lab on a Chip, 2014, (Featured as the inside back cover, Highlighted in ScienceDaily, EurekAlert, Phys.Org, etc, IF: 5.8).<\/li>\n\n\n\n<li>W. Kang, F. Yavari, M. Minary-Jolandan, J. Giraldo-Vela, A. Safi, R. McNaughton, V. Parpoil, H. Espinosa, Nanofountain Probe Electroporation (NFP-E) of Single Cells, 13(6), 2448-2457, Nano Letters, 2013, (Best Poster Award, Highlighted in ScienceDaily, Bio-Medicine, Technology Network, FierceDrugDelivery, National Institute of General Medical Sciences, etc, IF 14.9).<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"276\" height=\"186\" src=\"https:\/\/faculty.engineering.asu.edu\/kang\/wp-content\/uploads\/sites\/121\/2023\/05\/image-2.png\" alt=\"\" class=\"wp-image-37\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"385\" height=\"186\" src=\"https:\/\/faculty.engineering.asu.edu\/kang\/wp-content\/uploads\/sites\/121\/2023\/05\/image-3.png\" alt=\"\" class=\"wp-image-38\" srcset=\"https:\/\/faculty.engineering.asu.edu\/kang\/wp-content\/uploads\/sites\/121\/2023\/05\/image-3.png 385w, https:\/\/faculty.engineering.asu.edu\/kang\/wp-content\/uploads\/sites\/121\/2023\/05\/image-3-300x145.png 300w\" sizes=\"auto, (max-width: 385px) 100vw, 385px\" \/><\/figure>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p class=\"mb-2\">Micro\/nano-scale biotools for cell transfection and analysis are being developed to achieve cell-specific experimental capabilities and localized cell-tool interfaces. This allows for minimal perturbation to cells and unprecedented spatial resolution, which is essential for fundamental cell studies. The ability to precisely deliver molecules into single cells is of great interest to biotechnology researchers for advancing&#8230;<\/p>\n","protected":false},"author":228,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-34","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bionanotechnology - Wonmo Kang<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/faculty.engineering.asu.edu\/kang\/bionanotechnology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bionanotechnology - Wonmo Kang\" \/>\n<meta property=\"og:description\" content=\"Micro\/nano-scale biotools for cell transfection and analysis are being developed to achieve cell-specific experimental capabilities and localized cell-tool interfaces. This allows for minimal perturbation to cells and unprecedented spatial resolution, which is essential for fundamental cell studies. The ability to precisely deliver molecules into single cells is of great interest to biotechnology researchers for advancing...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/faculty.engineering.asu.edu\/kang\/bionanotechnology\/\" \/>\n<meta property=\"og:site_name\" content=\"Wonmo Kang\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-24T23:47:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/faculty.engineering.asu.edu\/kang\/wp-content\/uploads\/sites\/121\/2023\/05\/image-2.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/\",\"url\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/\",\"name\":\"Bionanotechnology - Wonmo Kang\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/wp-content\\\/uploads\\\/sites\\\/121\\\/2023\\\/05\\\/image-2.png\",\"datePublished\":\"2023-05-24T23:46:03+00:00\",\"dateModified\":\"2023-05-24T23:47:09+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/#primaryimage\",\"url\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/wp-content\\\/uploads\\\/sites\\\/121\\\/2023\\\/05\\\/image-2.png\",\"contentUrl\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/wp-content\\\/uploads\\\/sites\\\/121\\\/2023\\\/05\\\/image-2.png\",\"width\":276,\"height\":186},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/bionanotechnology\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Bionanotechnology\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/#website\",\"url\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/\",\"name\":\"Wonmo Kang\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/faculty.engineering.asu.edu\\\/kang\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Bionanotechnology - Wonmo Kang","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/faculty.engineering.asu.edu\/kang\/bionanotechnology\/","og_locale":"en_US","og_type":"article","og_title":"Bionanotechnology - Wonmo Kang","og_description":"Micro\/nano-scale biotools for cell transfection and analysis are being developed to achieve cell-specific experimental capabilities and localized cell-tool interfaces. 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