Hemorrhage inside the brain’s ventricles affects approximately 50% of premature newborns at gestational ages less than 33 weeks. As methods to limit this often fatal or disabling condition are developed, the need for early detection becomes crucial. Many cases involving low levels of intraventricular hemorrhage (< 50% ventricular filling) are missed by transcranial ultrasound. We have used spherical and realistic geometry phantoms to test the sensitivity of our different measurement protocols to ventricular blood.