Micro/nano-scale biotools for cell transfection and analysis are being developed to achieve cell-specific experimental capabilities and localized cell-tool interfaces. This allows for minimal perturbation to cells and unprecedented spatial resolution, which is essential for fundamental cell studies.
The ability to precisely deliver molecules into single cells is of great interest to biotechnology researchers for advancing applications in therapeutics, diagnostics, and drug delivery toward the promise of personalized medicine. The use of bulk electroporation techniques for cell transfection has increased significantly in the last decade, but the technique is nonspecific and requires high voltage, resulting in variable efficiency and low cell viability. Our lab is interested in developing a new biotool for cell analysis and manipulation.
